Chromatography columns, United Kingdom and Sweden,1975-1985

Made:
1975-1985 in Sweden and United Kingdom
maker:
Pharmacia Fine Chemicals AB

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15 Chromatography colomns, from Dr.E. Tuddenham's factor VIII research group at The Royal Free Hospital. Full view,
Science Museum Group Collection
© The Board of Trustees of the Science Museum

15 Chromatography columns, from Dr.E. Tuddenham's factor VIII research group at The Royal Free Hospital

Recombinant Factor VIII is an essential blood clotting component. Pioneering research into it was carried out in the early 1980s, headed by Dr E Tuddenham at The Royal Free Hospital, London. Recombinant Factor VIII was identified as a protein, known as an antihaemophilic globulin. These four chromatography columns were part of a set of 15 and were used by researchers to isolate such chemical compounds.

Haemophilia is an inherited disease in which the blood does not clot properly. It can lead to excessive bleeding and sometimes death. Factor VIII can help haemophilic blood to coagulate. The researchers also identified all the mutations causing Haemophilia A. They created the methods for tracking these through families. The columns are made of plastic and glass and were manufactured by companies in Sweden and the UK.

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Details

Category:
Laboratory Medicine
Object Number:
1994-1239
Materials:
glass, plastic
Measurements:
overall (largest): 1100 mm 50 mm,
overall (smallest): 390 mm 40 mm,
type:
chromatography equipment
credit:
Tuddenham, Edward G D
status:
Permanent collection

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